Treatment of chronic neuropathic pain: purine receptor modulation
نویسندگان
چکیده
منابع مشابه
Chronic neuropathic pain. Mechanisms, diagnosis, and treatment.
BACKGROUND The management of chronic pain represents a significant public health issue in the United States. It is both costly to our health care system and devastating to the patient's quality of life. The need to improve pain outcomes is reflected by the congressional declaration of the present decade as the "Decade of Pain Control and Research," and the acknowledgment in January 2001 of pain...
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OBJECTIVE The N-methyl-D-Aspartate (NMDA) receptor has been proposed as a primary target for the treatment of neuropathic pain. The aim of the present study was to perform a meta-analysis evaluating the effects of (individual) NMDA receptor antagonists on neuropathic pain, and the response (sensitivity) of individual neuropathic pain disorders to NMDA receptor antagonist therapy. DESIGN PubMe...
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ژورنال
عنوان ژورنال: Pain
سال: 2020
ISSN: 0304-3959,1872-6623
DOI: 10.1097/j.pain.0000000000001857